Features

*Molecular biology grade

*Tested and certified for in vivo imaging

Description & Application

Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase  utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.

Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through bioluminescence imaging. Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Quality Control

4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid potassium salt

Formula: KC11H7N2O3S2

MW: 318.42 g/mol

Color: Light yellow powder

Purity: >99% pure.)

Package Size

0.1g, 1g

Store at

-20°C; proof of light

Cat No. Size Price
Luciferin, potassium salt LFN100 100mg US$104
LFN-1G 1g US$490

 


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